Immunization Information

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Live Intranasal Influenza Vaccine
What you need to know

1. Why get vaccinated?

Influenza ("flu") is a contagious disease.

It is caused by the influenza virus, which spreads from person to person through coughing or sneezing.

Other illnesses have the same symptoms and are often mistaken for influenza. But only the influenza virus can cause influenza.

Anyone can get influenza. For most people, it lasts only a few days. It can cause:

Some people get much sicker. Influenza can lead to pneumonia and can be dangerous for people with heart or breathing conditions. It can cause high fever and seizures in children. Influenza kills about 36,000 people each year in the United States, mostly among the elderly.

Influenza vaccine can prevent influenza.

2. Live, attenuated influenza vaccine (nasal spray)

There are two types of influenza vaccine:

Live, attenuated influenza vaccine (L.A.I.V.) was licensed in 2003. L.A.I.V. contains live but attenuated (weakened) influenza virus. It is sprayed into the nostrils rather than injected into the muscle. It is recommended for healthy children and adults from 5 through 49 years of age, who are not pregnant.

Inactivated influenza vaccine, sometimes called the "flu shot," has been used for many years and is given by injection. This vaccine is described in a separate Vaccine Information Statement.

Influenza viruses are constantly changing. Therefore, influenza vaccines are updated every year, and annual vaccination is recommended.

For most people influenza vaccine prevents serious influenza-related illness. It will not prevent "influenza-like" illnesses caused by other viruses.

It takes about 2 weeks for protection to develop after vaccination, and protection can last up to a year.

3. Who can get L.A.I.V.?

Live, intranasal influenza vaccine is approved for healthy children and adults from 5 through 49 years of age, including those who can spread influenza to people at high risk, such as:

Influenza vaccine is also recommended for anyone else who wants to reduce their chance of getting influenza.

L.A.I.V. may be considered for:

4. Who should not get L.A.I.V.?

LAIV is not licensed for everyone. The following people should check with their health-care provider about getting the inactivated vaccine (flu shot).

Inactivated influenza vaccine (the flu shot) is the preferred vaccine for people (including health-care workers, and family members) coming in close contact with anyone who has a severely weakened immune system (that is, anyone who requires care in a protected environment).

Some people should talk with a doctor before getting either influenza vaccine:

5. When should I get influenza vaccine?

The best time to get influenza vaccine is in October or November, but L.A.I.V. may be given as soon as it is available. Influenza season usually peaks in February, but it can peak any time from November through May. So getting the vaccine in December, or even later, can be beneficial in most years.

Most people need one dose of influenza vaccine each year. Children younger than 9 years of age getting influenza vaccine for the first time should get 2 doses For L.A.I.V., these doses should be given 6-10 weeks apart.

L.A.I.V. may be given at the same time as other vaccines.

6. What are the risks from LAIV?

A vaccine, like any medicine, could possibly cause serious problems, such as severe allergic reactions. However, the risk of a vaccine causing serious harm, or death, is extremely small.

Live influenza vaccine viruses rarely spread from person to person. Even if they do, they are not likely to cause illness.

L.A.I.V. is made from weakened virus and does not cause influenza. The vaccine can cause mild symptoms in people who get it (see below).

Mild problems:

Some children and adolescents 5 through 17 years of age have reported mild reactions, including:

Some adults 18 through 49 years of age have reported:

These symptoms did not last long and went away on their own. Although they can occur after vaccination, they may not have been caused by the vaccine.

Severe problems:

6. What if there is a moderate or severe reaction?

What should I look for?

What should I do?

Or you can file this report through the VAERS web site at vaers.hhs.gov, or by calling 1-800-822-7967.

VAERS does not provide medical advice

7. The National Vaccine Injury Compensation Program

In the rare event that you or your child has a serious reaction to a vaccine, a federal program has been created to help you pay for the care of those who have been harmed.

For details about the National Vaccine Injury Compensation Program, call 1-800-338-2382 or visit the program's website at www.hrsa.gov/vaccinecompensation

8. How can I learn more?

U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES
Centers for Disease Control and Prevention
National Immunization Program

Disclaimer: This document is an html version of the CDC's pdf brochure found here. While every effort is made to create an exact duplicate, errors may have occurred in translation from pdf to html.

For your child's health and safety please do not make any vaccination decisions without first consulting your health care provider.